Some of these copies may by chance have the right kinds of errors in their genetic code to become variants of concern, although the mutation rate of this coronavirus is quite low. "There can be no doubt," Vanden Bossche asserts, "that lack of exposure due to stringent containment measures implemented as of the beginning of the pandemic has not been beneficial to keeping peoples innate immune system well trained. He held adjunct faculty appointments at universities in Belgium and Germany. Published: 23 Mar 2021. Potentially leaky vaccine but stellar disease reduction. Hes also conflating innate immune responses with specific immune responses induced by either infection or vaccination. Therefore he has zero credibility when it comes to advising the public or anyone else about how to avoid negative effects of mass vaccination. Dont you see? The role of spike protein variability inT cell immunity is likely to be elucidated in experimental studies in the next few months; a priori, the enhanced repertoire of T cell epitopes makes the loss of cytotoxic activity or recognition improbable. You can throw the same virus at your innate immune system and it will not remember it. He asserts that his statements "are based on nothing else but science." The way to avoid this purported calamity, Vanden Bossche asserts, is for scientists to pay more attention to his own invention a "universal vaccine" that uses the body's innate immune system to kill SARS-CoV-2. He also points out that there is new research challenging the previous dogma that leaky vaccines always select for more virulent strains of pathogen and cannot produce herd immunity. As a creative thinker, innovator, entrepreneur and visionary, Geert has been invited to speak at multiple international congresses. Even so, concern about immune escape is one reason why Pfizer, BioNTech, and Moderna used the entire SARS-CoV-2 spike protein, rather than specific segments of it that might serve as antigens, so that the polyclonal antibody immune response generated would be broad and unlikely to be escaped with single mutationsor even multiple mutations. This growing threat has led what many senior public health officials in the UK and the U.S. to describe as the post-antibiotic apocalypse and the end of modern medicine. It is estimated that 50,000 annual deaths occur in Europe and the U.S. from infections that antibiotics have lost the power to treat. So in fewer than 80 years, we have reached the point at which, for example, with prosthetic surgery, wards are being closed down, patients are being sent home, and operations are no longer possible, because once the prosthesis becomes infected with such bacteria, it is virtually impossible to get rid of them. GEERT VAN DEN BOSSCHE THE LAST POST He is a super expert in vaccine development. Where do we plant our next step? It is precisely this type of highly specific, high affinity Abs that current Covid-19 vaccines are inducing. _). It has been observed that over time Mareks disease virus has become more virulent, and this has been attributed classically to a leaky vaccine effect. After all, as Nirenberg and the review article I quoted above note, while it is true that variants of concern demonstrate reduced antibody neutralization, we do not as yet have an absolute correlate regarding how high an antibody level is required to be protective, making the practical meaning of this observation difficult to determine. There is a reason why a new flu vaccine is made each year: the influenza virus drifts and shifts and the vaccine needs to be reformulated to be a better match for the specific viruses that are predicted to be common during the next flu season. And if you have been at this for a while, like Dr. David Gorski who has followed and denounced the anti-vaccination movement since time immemorial, you may even pick up on similarities with the disgraced Andrew Wakefield. This strategy is based on vaccines that target the adaptive arm of our immune system, the same principle that allowed us to slay smallpox and bring polio and measles down to their knees. We can hardly say we didnt know or were not warned. Its a very interesting question. Bret speaks with Dr. Geert Vanden Bossche in Bath, England, together for the COVID Better Way Conference 2022. Read full document here: https://t.co/DPDFlg4U45 pic.twitter.com/TISexYqyTq, Geert Vanden Bossche (@GVDBossche) March 13, 2021. These public commentators, often bedazzled with advanced degrees, have painted themselves as brave mavericks escaping from the mainstream herd to denounce the cataclysmic consequences of public health measures. Before this open letter, I hadnt recalled ever having heard of Dr. Vanden Bossche before, so I looked around. For example, just before the three-minute mark in the video interview of Vanden Bossche by McMillan, Vanden Bossche indicates hes a long-time vaccine developer. Because, he says, the vaccines are imperfect, they will allow the virus to keep being transmitted from person to person and thus mutate inside of us, until a dangerous new variant emerges. Visit Geert at https://www.voiceforscienceandsolidarity.org/ and stay updated on his latest blogs, projects, and videos. But, he said, Vanden Bossche's arguments "take a little bit of truth and then add a whole lot of misrepresentation.". Saltar al contenido principal.es. Selecting targeted mutations in the S protein is, therefore, the way to go in order for the virus to enhance its infectiousness in candidates that are prone to geting [sic] the disease because of a transient weakness of their innate immune defense. Word Wise helps you read harder books by explaining the most challenging words in the book. By educating these cells in ways that enable them to durably recognize and target Coronavirus-infected cells, our immune system could be perfectly armed for a targeted atack to the universe of Coronaviruses prior to exposure. No need to panic. Vanden Bossche's scientific argument in broad terms is that the current COVID-19 vaccines, through a mechanism analogous to antibiotic resistance, will create mutant variants of the virus that escape the protection of those vaccines. Hola Elige tu direccin Todos los departamentos. Thankfully, there is a vaccine against it, but over time, newer and more virulent strains of the virus have been detected, and this made scientists think it was because the vaccine was leaky, that it did not allow the chicken to mount a good enough immune response. Dr. Bossches concern about imperfect vaccines allowing the virus to mutate should be dwarfed by the much larger, evidence-based worry of allowing the virus to mutate inside of unvaccinated people. When you read Dr. Bossches open letter, you should pick up on the Galileo gambit, which is when you infer that because Galileo was laughed at but ultimately correct, your laughable idea must also be correct. On today's show Dr. Ben discusses with Dr. Geert how we got it wrong by implementing a mass vaccination campaign in the middle of a pandemic. Edward Nirenberg, a science blogger who addressed Dr. Bossches claims in great detail, points to Mareks disease. Please try again. Bossche claims that the same thing will happen with the coronavirus. Please try again. But wait, says Dr. Vanden Bossche. The ongoing phase 3 trial of an adenovirus-vectored spike-based vaccine (Johnson & Johnson, NCT04505722) in South Africa, where the 501Y.V2 (B.1.351) strain with the Glu484Lys substitution is rapidly replacing pre-existing variants,11 might provide an opportunity to examine this question. Geert Vanden Bossche, DMV, PhD, independent virologist and vaccine expert, . Reviewed in Germany on February 22, 2023, Learn more how customers reviews work on Amazon. Perhaps no more tired a trope exists in the world of faux cures than the "I have found a problem that no other scientist in the world has thought of and only my untested and unproven cure can stop it" gambit. After his career in Academia, Geert joined several vaccine companies (GSK Biologicals, Novartis Vaccines, Solvay . As previously explained (see contribution: 'Unravelling the complexity of Covid-19 vaccination shaped by mass vaccination'), this beneficial effect will wane quite (Truly, those were simpler times.). Dr. Vanden Bossche has also taken to social media to air his concerns, and his message has been enthusiastically embraced by antivaxxers: Lets just say this. MASS VACCINATION of the ELDERLY. It remembers tiny invaders and fights them back with more vigour each time. And Dr. Vanden Bossches concerns are based on Science! Maybe. I'm glad I finally know. The solution to that risk is to vaccinate as many people as quickly as possible, thereby reducing both transmission of the virus and the number of environments in which mutations could occur. "The new variants are a production and result from the vaccination. Vanden Bossche has been able to avoid allegations of peddling such a cure at least in the credulous anti-vaccine community because his resume legitimately includes stints at companies or initiatives involved in vaccine development, including The Bill and Melinda Gates Foundation. you get antibodies that are no longer able to completely neutralize the virus -we are seeing more and more that mass vaccinations can lead to resistance . Natural Abs are not germ-specific whereas acquired Abs are specifically directed at the invading pathogen. What would you do? Whats particularly dangerous about Dr. Vanden Bossches misinformation is that, on the surface, he appears to be a vaccine expert, whom antivaxxers touting his open letter (and all the follow-up science hes been Tweeting and posting to his website) have been describing as a worlds expert in vaccines. Calculations for herd immunity consider two sources of individual immunity vaccines and natural infection. However, Dr. Vanden Bossches claims to have worked with the Gates Foundation, GAVI, and other vaccine-related enterprises does seem to be legitimate, which makes me wonder: Has he gone crank or is he a grifter? [Editors note: Scott Gavura had circumstances pop up that prevented him from producing a post for today. After his career in Academia, Geert joined several vaccine companies (GSK Biologicals, Novartis Vaccines, Solvay Biologicals) to serve various roles in vaccine R&D as well as in late vaccine development. Were in a race with the new variants, Sara Del Valle, a computational epidemiologist at the Los Alamos National Laboratory in New Mexico explained in a March 2021 feature in the scientific journal Nature. Follow Us : Tags Coronavirus In scenario #1, you get rid of vaccines and lockdowns and allow the virus to spread, practically unimpeded, through the population, killing more and more people and leaving many with long-term health consequences. The technology enables the development of universal vaccines educating the host immune system to redirect immune targeting away from canonical antigens to a widely divergent spectrum of vitally vulnerable pathogen-derived self-mimicking antigens, irrespective of MHC polymorphism. If we, human beings, are committed to perpetuating our species, we have no choice lef [sic] but to eradicate these highly infectious viral variants. Even if it were evolving resistance, once again, the answer would be to reformulate the vaccine in order to include the altered antigens, the same conclusion made when considering the possibility that B. pertussis was evolving resistance or that evolutionary drift was leading to the predominance of strains not covered by the vaccine. Vanden Bossche is using an eerily similar argument about COVID-19 vaccines and SARS-CoV-2, he wrote for the blog Science-Based Medicine, to the one used by Wakefield about [the measles-mumps-rubella] vaccine and measles. In any case, I got a particularly strong brave maverick vibe from this passage: While there is no time to spare, I have not received any feedback thus far. The Inescapable Immune Escape Pandemic : Vanden Bossche MD Phd, Geert: Amazon.es: Libros. And lest we forget: the variants of concern making headlines now arose before we had any vaccine against the coronavirus. One of his topics is labeled, "Why mass vaccinaton amidst a pandemic creates an irrepressible monster." In the first two letters alone, he uses some variation of the phrase "it is reasonable to assume" at least seven times. But what about asymptomatic transmission? Last Monday, I provided international health organizations, including the WHO, with my analysis of the current pandemic as based on scientifically informed insights in the immune biology of Covid-19. Statement by Geert Vanden Bossche, DMV, PhD, independent virologist and vaccine expert, formerly employed at GAVI and The Bill & Melinda Gates Foundaton. In my new book, The inescapable immune escape pandemic, I am sharing my insights and perspectives on how the Covid-19 pandemic continues to evolve. "Natural infection kills. David H. Gorski, MD, PhD, FACS is a surgical oncologist at the Barbara Ann Karmanos Cancer Institute specializing in breast cancer surgery, where he also serves as the American College of Surgeons Committee on Cancer Liaison Physician as well as an Associate Professor of Surgery and member of the faculty of the Graduate Program in Cancer Biology at Wayne State University. Geert Vanden Bossche . Truly, in the age of COVID-19, everything old is new again, and the antivaccine grift continues. Highlighting the principle of using a prophylactic vaccine in the midst of a pandemic. Today we are in . Waiting for Vanden Bossche's "universal vaccine" is no way to win such a race. This is an absurdly counterproductive solution if Vanden Bossche were truly concerned about variants. Both men have taken an ethical stand to focus on science and not be afraid to share their expertise. Alex Kasprak is an investigative journalist and science writer reporting on scientific misinformation, online fraud, and financial crime. "Cause Unknown": The Epidemic of Sudden Deaths in 2021 & 2022 (Childrens Health Defense), Principles for Dealing with the Changing World Order: Why Nations Succeed and Fail, There are 0 reviews and 0 ratings from the United States, This outstanding body of work that explains the virology of the pandemic the understanding of Vaccines how they work the shortcomings of public health. ES. It is caused by a herpesvirus and it gives chickens a number of health problems, including cancer. Hes also started making rounds on the podcast/vlog interview circuit: You can watch yesterday's interview with Philip McMillan here: https://t.co/sx9fxpsyHg Thanks for all your support, we will need it.
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