Dermatoses resulting from physical factors. This means that, as youre exposed to UV light, your skin can build up a UV tolerance. Sunscreens containing the broad-spectrum UVA absorber, Mexoryl SX, prevent the cutaneous detrimental effects of UV exposure: a review of clinical study results. Doctors think it is a type of delayed allergic reaction. It does not seem to be associated with systemic disease or drugs. [4], Typically, the first episode develops in the spring following the first exposure to intense sun. FOIA This hormone may prevent UV radiation from suppressing the skins immune responses. 2014 Aug;134(8):2290-2293. doi: 10.1038/jid.2014.160. See additional information. A study across Europe found that PMLE affects as much as 18 percent of the population there. Skin diseases due to physical and chemical causes", https://en.wikipedia.org/w/index.php?title=Polymorphous_light_eruption&oldid=1127125983, Skin conditions resulting from physical factors, Pages containing links to subscription-only content, Creative Commons Attribution-ShareAlike License 3.0, Shortly after sun exposure in people younger than age 30-years, This page was last edited on 13 December 2022, at 01:14. Please enable it to take advantage of the complete set of features! The sun-protective measures you take to prevent polymorphous light eruption also lower your risk of skin cancer. Reported to be more common at higher altitudes compared to sea level regions. PLE can look similar to other rashes, such as the rash that occurs in people with lupus erythematosus. It is one of the most common sun-related skin problems and is most common among women and among people from northern climates who are not regularly exposed to the sun. Polymorphic light eruption is also known as polymorphous light eruption and prurigo aestivalis. DermNet provides Google Translate, a free machine translation service. PLE causes small bumps or raised plaques on the skin. [22], Generally, PLE resolves without treatment; also, PLE irritations generally leave no scar. Before Polymorphous light eruption (PMLE) is an acquired disease and is the most common of the idiopathic photodermatoses. The test is repeated on the same site daily for 3 days and the area examined to detect the typical rash. A rash can be a symptom of many different conditions. Plasmacytoid dendritic cells and T regulatory cells predominate. Oakley AM, et al. A provocative test in which UV radiation is used to confirm the diagnosis. What to wear to protect your skin from the sun. Consider wearing clothing designed to provide sun protection. Exp Dermatol. Centers for Disease Control and Prevention (CDC). [18], Sunlight has been documented to trigger numerous skin conditions and the confusing terminology and categorisation previously has made the correct diagnosis and subsequent treatment difficult. Several hours to days later, an irritablerash appears on areas newly exposed to the light such as the dcolletage, forearms, backs of hands, lower legs and feet. ncbi.nlm.nih.gov/pmc/articles/PMC7379702/, ncbi.nlm.nih.gov/pmc/articles/PMC8323194/, ncbi.nlm.nih.gov/pmc/articles/PMC6139322/, dermnetnz.org/topics/polymorphic-light-eruption, nhs.uk/conditions/polymorphic-light-eruption/, aad.org/public/everyday-care/sun-protection/shade-clothing-sunscreen/what-to-wear-protect-skin-from-sun, Every Sunscreen Question You Have, Answered, Debra Sullivan, Ph.D., MSN, R.N., CNE, COI. It is not always possible to completely prevent PLE in people who are prone to it. We avoid using tertiary references. Polymorphous light eruption, also known as "sun allergy" or "sun poisoning" is the most common photosensitivity. Polymorphic light eruption is a fairly common skin rash triggered by exposure to sunlight or artificial ultraviolet (UV) light. Note that this may not provide an exact translation in all languages, Home Polymorphous light eruption: clinic aspects and pathogenesis. Unable to load your collection due to an error, Unable to load your delegates due to an error. Photodermatol. Follow care instructions on the label of UV-blocking clothes to maintain their protective feature. PMLE can appear on any part of your body exposed to UV light, although it rarely appears on your face. Treatment of polymorphous light eruption usually isn't needed because the rash usually goes away on its own within 10 days. government site. This content does not have an English version. and transmitted securely. 1987 Mar;88(3 Suppl):32s-38s. Elsevier; 2020. https://www.clinicalkey.com. [3] The bumps may become small blistersor plaques and may appear bloody,[3]often healing with minimal scarring. Epub 2015 Jul 30. Accessed Dec. 9, 2021. It may affect up to 15% of people worldwide. https://www.aad.org/media/stats-sunscreen. This condition causes a red, itchy rash to form soon after you've been in the sun or exposed to artificial UV rays. How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, https://dermnetnz.org/topics/polymorphic-light-eruption, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8323194/, https://onlinelibrary.wiley.com/doi/10.1111/phpp.12093, https://www.ncbi.nlm.nih.gov/books/NBK430886/, https://www.nhs.uk/conditions/polymorphic-light-eruption, https://www.aocd.org/page/PolymorphousLightE, https://www.skincancer.org/skin-cancer-prevention/sun-protection/, https://www.aad.org/public/everyday-care/sun-protection/shade-clothing-sunscreen/what-to-wear-protect-skin-from-sun, https://www.skincancer.org/blog/what-you-need-to-know-about-photosensitivity/, One-hour endoscopic procedure could eliminate the need for insulin for type 2 diabetes, New clues to slow aging? It also occurs in some patients treated for inflammatory skin diseases with phototherapy, when it may appear on the trunk and proximal limbs. Disclaimer. This should only be done by a professional. The following factors must be considered when determining pathogenesis and when implementing protective measures: UV radiation usually creates an immunosuppressive response in the skin, however, patients with PMLE may have a reduction in this normal response. Blood tests might also be used to rule out other conditions. [10] It is also thought that skin microbiome or microbial elements could be involved in pathogenesis of the disease [13][14], PLE can be provoked by UVA or UVB (chief cause of sunburn) rays, meaning it can be triggered even by sunlight through glass. Anyone can have PMLE, but its more common for people with lighter color skin, particularly Fitzpatrick skin type 1. Disclaimer. Lesions may vary from patient to patient; however, spontaneous resolution (on cessation of sun exposure) is often a unifying trait. Using high SPF, broad-spectrum sunscreen, and wearing protective clothing helps minimize UV light exposure. Kittler H, Hnigsmann H, Tanew A: Antinuclear antibodies in patients with polymorphic light eruption: a long-term follow-up study. Therapy is based mainly on topical or systemic corticosteroids. Accessed Nov. 12, 2021. An official website of the United States government. Gibson LE (expert opinion). DermNet does not provide an online consultation service. Join. PMLE is about four times more common in women than in men. In PMLE patients, UV radiation leads to an increased amount of CD4 and CD8 T lymphocytes, and an increased inflammatory response in the epidermis and dermis. [10], As sun exposure is avoided, vitamin D levels may fall and hence supplements are sometimes advised. However, this study was small. Polymorphic light eruption codes and concepts, 238525001, 79372000, 238525001, 6618004, 54116000, 84036008, 51048002. 1 mo. Recently appearing lesions may show neutrophils. Emergency Nurse. [6], It has been suggested that an undefined endogenous or exogenous photo-allergen may trigger a delayed immune reaction resulting in PLE. Too much sun exposure, smoking, allergic reactions, and even lip sucking can lead to. You can learn more about how we ensure our content is accurate and current by reading our. Patterson JW. window.__mirage2 = {petok:"qA58IQ768GeOLKFViL7kQqLnoC_jvex_EJRsbmd4PEw-1800-0"}; Because PMLE is more prevalent in women than men, it is hypothesized that there is a hormonal component to its pathogenesis. There is often impressive papillary dermal oedema (figures 1, 2, 3). The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Willan House, 4 Fitzroy Square, London, W1T 5HQ | [email protected] | +44 (0)020 7383 0266 Polymorphous light eruption (PMLE). Is there a generic alternative to the medicine you're prescribing me? Ultraviolet-radiation-induced erythema and suppression of contact hypersensitivity responses in patients with polymorphic light eruption. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. Its also called polymorphic light eruption and prurigo aestivalis. doi: 10.1111/1523-1747.ep12468916. National Library of Medicine [7] The resulting itch can cause significant suffering. Polymorphic light eruption is the most common form of immunologically mediated photosensitivity dermatoses. sharing sensitive information, make sure youre on a federal PLE commonly affects people for many years, but most peoples symptoms improve or disappear over time. Causes. If you have a rash in addition to other symptoms that are more serious, you may need emergency care. Long-term course of polymorphic light eruption: A registry analysis. Morphology variesbetweenindividualsand can include macules, vesicles, lichenoid plaques, prurigo papules and targetoid lesions resembling erythema multiforme. [15] Hence, it is less common near the equator. Abstract. J Am Acad Dermatol. It lasts for up to 2 weeks, healing without scarring. More people experience polymorphic light eruption at high altitude than at sea level.[1]. [4], PLE is more common in young adults and has a female preponderance[5] with a ratio of 2:1 female-to-male. Low-dose narrowband UV-B and other forms of phototherapy undertaken in late winter or early skin can reduce the incidence and severity of polymorphous light eruption. Direct immunofluorescence testing is negative. False negative responses occur in 10% to 40% of tested individuals. The photo antigen that triggers this response is currently unknown. [5], Photosensitivity is also found in some of the porphyrias. Kliegman RM, et al. official website and that any information you provide is encrypted For polymorphous light eruption, some basic questions to ask your health care provider include: Your health care provider will ask you a number of questions about your symptoms and your medical history, such as: Avoid sun exposure whenever possible. PLE symptoms typically appear around 2 hours after sun exposure and last for several days before improving on their own. In short, jock itch can spread between, Keloids can appear on your ear in response to any type of wound, including a piercing. [1][2], UV-A is theusualpart of the electromagnetic spectrum that provokes polymorphous light eruption (75% to 90%).
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